A Set of Graduate Placements for Chinese Returnees

Project Background


One of our partners in the BioScience Sector is hiring full-time staff in China. These positions are open to Chinese nationals who are studying at western universities and about to graduate, or have just graduated from their universities and are looking for opportunities in China.


Salary: Internship Period: RMB1800/m; Fulltime Offer: RMB5000-7000; RMB9000-12000(PHD)


Host Company Profile


This company is a life science company based in Chengdu, China. It was founded by people with extensive scientific and managerial experience in pharmaceutical, CRO and related industries. The formation of the company has received major investment from China Chengdu Import and Export Group Co. Ltd, and enterprise grant support from Chengdu High Tech Zone. It is an innovation-driven and customer-focused company which has established a unique platform for early drug discovery re-search. With a focus on hit identification and lead generation during the early phase of drug discovery R&D, this company aims to be a leading provider in progressing projects from target to leads stage. To this end it has established a core platform consisting of high quality, large DNA encoded compound libraries and research capabilities in protein expression and purification, in vitro screening and affinity selection, chemical library design and synthesis, and medicinal chemistry. It also provides other biological reagents and services to support drug discovery research.


See below for details. For more information and to apply, contact us. Read information about the Chinese Returnee program before you apply.



Position Description

Biological research and development staff (Enzymatic detection)


Responsibilities


  • Execute protein activity detection methods, analyze the in vitro activity of compounds, assist in analyzing the data of structure-activity relationships, assist in promoting R&D projects.

  • Write and edit research reports and standard operating procedures in English


Requirements


  • Understand basic enzymology theory, especially enzymatic reaction kinetics; understand in vitro enzymatic methods for the detection of drugs, including fluorescence detection, chemiluminescence, ELISA and time-resolved fluorescence.

  • Preference given to candidates with good knowledge of biophysical detection methods e.g. SPR, ITC, TSA.

  • Experience preferred.

  • Undergraduates should attach their academic transcripts; graduates should attach their research summaries.

  • Skilled at reading English-language scientific literature.

Biological R&D (Protein purification)


Responsibilities


  • Manage the expression and purification of molecular cloning and E. Coli systems.

  • Manage the large scale expression of insect and mammal cells and the construction of stable cell lines.


Requirements


  • Master’s degree and above in cell biology, molecular biology or other related fields.

  • Good knowledge of protein expression and purification, protein crystal, experience with insect and mammal cell cultivation and expression.

  • Passionate about technology and research.

Advanced biological research and development staff (molecular biology)


Responsibilities


  • Design molecular biology experimental independently, solve the problems of DNA in a chemical reaction

  • Conduct and improve various molecular biology experiments, including cloning, plasmid extraction, purifying PCR products, PCR amplification, identification of electrophoresis, DNA quantification

  • Find and solve technology problems in the development process; discuss these with the biological technology unit.

  • Develop new technology and methods, improve SOP

  • Write academic reports, write and edit the English-language experimental record and SOP

  • Other tasks connected with technology development.


Requirements


  • Master’s degree and above in biotechnology, bioinformatics, molecular biology or other related major; at least two years of work experience.

  • Master basic skills of molecular biology well, especially the structure of DNA and its stability

  • Proficient in using genome databases, nucleic acid sequence databases, etc. Be familiar with common bio-websites.

  • Able to understand English-language scientific literature.

  • Responsible and logical; with good time-management skills.

  • Independent problem-solver.

  • Good team player.

Biological research and development staff (cell biology)


Responsibilities


  • Design cellular level drug evaluation experiments, optimize and verify methods and use these to write up SOP.

  • Take responsibility for Efficacy evaluation tests of Compound levels, write official experimental records and reports.

  • Take responsibility for maintaining cell bank reserves.

  • Find and solve technology problems during the development process.

  • Support project manager in finishing cell function analysis in related projects.


Requirements


  • Master’s degree and above in cell biology or molecular biology, with two years’ experience in the field.

  • Good knowledge of the theoretical basis of cell biology.

  • Experience in cultivating mammal cells with skills including cell cultivation, cell transfection, stable cell line screening, flow cytometry, molecular cloning.

  • Background or work experience in cell-level screening of drugs preferred.

  • Good data analysis skills.

  • Understand English-language scientific literature.

  • Responsible, careful and good team player.

Biological research and development staff (molecular biology)


Responsibilities


  • Design molecular biology experimental independently, solve the problems of DNA in a chemical reaction.

  • Conduct and improve various molecular biology experiments, including cloning, plasmid extraction, purifying PCR products, PCR amplification, identification of electrophoresis, DNA quantification.

  • Find and solve technology problems in the development process; discuss these with the biological technology unit.

  • Develop new technology and methods, improve SOP.

  • Write academic reports, write and edit the English-language experimental record and SOP.

  • Other tasks connected with technology development.


Requirements


  • Master’s degree and above in biotechnology, bioinformatics, molecular biology or other related major; at least two years of work experience.

  • Master basic skills of molecular biology well, especially the structure of DNA and its stability.

  • Proficient in using genome databases, nucleic acid sequence databases, etc. Be familiar with common bio-websites.

  • Able to understand English-language scientific literature.

  • Responsible and logical; with good time-management skills.

  • Independent problem-solver.

  • Good team player.

Biological research and development staff (DNA encoding direction)


Responsibilities


  • Encode small molecule library DNA.

  • Encode DNA according to SOP, assist in developing new encoding technology.

  • Find and solve technology problems in the development process; and discuss these with the bio-technology unit.

  • Write and edit research English-language reports and SOP.


Requirements


  • Degree in biological sciences, biochemistry, molecular biology or related fields.

  • Associate degree and above, experience preferred.

  • Working experience in DNA molecular biology preferred.

  • Critical and independent thinker.

  • Skilled at literature review.

  • Fluent written English.

  • Responsible scientist with good experimental skills.

  • Good team player.

Biological research and development staff (Drug Screening)

Responsibilities


  • Handle affinity screening of target proteins done by DNA coding compound libraries.

  • Assist in advancing R&D projects.

  • Find and solve technology problems in the development process.

  • Support project manager with finishing drug affinity screening work in related programs.

  • Responsible for technical support and customer exchanges.

  • Write and edit English-language research reports and SOP.


Requirements


  • Master’s degree and above in molecular biology, proteomics, enzymology, pharmacy or other bio-related subjects.

  • Good understanding of the basic theory of enzymology, interactions between proteins and small molecules, quantitative PCR, gel electrophoresis, Western Blot, ELISA, etc.

  • Able to do basic in vitro enzymatic detection, experience in IC50 Detection, enzyme kinetic parameters (Km,KD, etc.) preferred.

  • Experience in drug screening or related fields preferred.

  • Skilled at reading and writing English-language scientific literature.

Advanced computational chemistry research and development staff

Responsibilities


  • Design and optimize small molecule inhibitors.

  • Do virtual screening based on ligands and structures.

  • Establish QSAR models and data analysis.

  • Assist with surveying for new projects.


Requirements


  • Ph.D. in chemical or pharmaceutical fields.

  • Proficient in molecular docking and virtual screening.

  • Proficient in using simulation software such as Discovery studio, MOE, Schrodinger and PyMol.

  • Proficient in at least one major programming language.

  • Fluent oral and written English.



Advanced Analytics R & D staff

Responsibilities


  • Lead the efforts for analytical development studies within the ARD department; act as project leader in analytical development projects.